Answer
Oct 03, 2024 - 01:40 PM
The major adverse effect of acitretin is teratogenicity, meaning it can cause severe birth defects if taken during pregnancy. Additionally, it can lead to other side effects such as hyperlipidemia, hepatotoxicity, and mucocutaneous effects like dry skin and lips. Women of childbearing potential must use effective contraception during treatment and for a period after discontinuation due to the drug's long half-life.