Answer
Apr 04, 2025 - 03:26 PM
Canagliflozin is associated with several warnings and precautions. It can increase the risk of lower limb amputations, particularly in patients with a history of cardiovascular disease or existing foot ulcers. Other potential risks include ketoacidosis, acute kidney injury, urosepsis, and serious urinary tract infections. It's also important to monitor for signs of hypotension and hyperkalemia, especially in patients with renal impairment or those taking diuretics.