Answer
May 21, 2025 - 11:43 AM
Opicapone is typically taken at night because it works as a catechol-O-methyltransferase (COMT) inhibitor, which helps to prolong the effect of levodopa in managing Parkinson's disease symptoms. Taking it at night can help to stabilize dopamine levels overnight, potentially reducing morning "off" periods and improving overall symptom control during the day. Additionally, nighttime dosing can help minimize certain side effects that might occur if taken during the day.