Answer
May 22, 2025 - 09:49 AM
Ketoprofen, a nonsteroidal anti-inflammatory drug (NSAID), carries a black box warning due to the risk of serious cardiovascular and gastrointestinal events. It may increase the risk of heart attack, stroke, and serious gastrointestinal issues like bleeding, ulceration, and perforation of the stomach or intestines. These risks can be fatal and may occur without warning, especially in older adults.