Answer
Jun 19, 2025 - 12:03 PM
The best time to take Cortef (hydrocortisone) is typically in the morning, as it aligns with your body's natural cortisol production, which peaks early in the day. This timing can help minimize potential side effects and better mimic your body's natural rhythm. However, it's crucial to follow your healthcare provider's specific instructions, as individual needs can vary.
