Is Sentinel Spectrum safe for all dog breeds? Sentinel Spectrum (Milbemycin Oxime / Lufenuron / Praziquantel)

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Is Sentinel Spectrum safe for all dog breeds? Sentinel Spectrum (Milbemycin Oxime / Lufenuron / Praziquantel)

Status: Open Oct 23, 2025 - 10:27 AM

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Oct 23, 2025 - 10:27 AM

Sentinel Spectrum is not safe for dogs with the MDR1-allele mutation, which includes breeds like Australian Shepherds, Collies, and Shelties. The MDR1 (Multi-Drug Resistance 1) gene mutation can make certain breeds more sensitive to medications, which is important to know to avoid adverse reactions.