Answer
Oct 23, 2025 - 11:03 AM
The best place to rub estradiol cream is usually on clean, dry, unbroken skin of the lower trunk or thighs, such as the inner thighs or lower abdomen, unless your doctor gives different instructions. Avoid applying it to the breasts, face, or irritated skin, and wash your hands after application. Always follow your healthcare provider’s guidance for the specific product you are using.
