Answer
Nov 19, 2025 - 12:05 PM
The 5:2:1 rule for Parkinson's disease is a clinical guideline used to identify patients who may benefit from advanced therapies. It suggests considering referral if a patient takes 5 or more doses of levodopa per day, has 2 or more hours of "off" time daily, or experiences 1 or more hours of troublesome dyskinesia each day. This rule helps clinicians recognize when standard treatments may no longer be sufficient.
