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Feb 13, 2026 - 09:55 AM
We’ve provided several answers to questions related to Comfortis Chewable Tablets (Spinosad) , see some other helpful Q&A related to this product.
Question: How does spinosad work to kill fleas?
Answer: Spinosad works by activating nicotinic acetylcholine receptors in fleas, causing involuntary muscle contractions, paralysis, and death. This targeted action helps eliminate fleas efficiently and reduces the risk of resistance.
Question: What is the recommended minimum monthly dosage for cats?
Answer: The recommended minimum dosage for cats is 22.5 mg per pound per month. Accurate dosing helps maximize the benefits of flea prevention while reducing risks.
Question: What is the minimum age for dogs and puppies to use this product?
Answer: Dogs and puppies must be at least 14 weeks old before they can use this product. Using the product only on appropriately aged animals minimizes risk to growing puppies.
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