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Apr 15, 2026 - 03:44 PM
We’ve provided several answers to questions related to Tofranil (Imipramine) , see some other helpful Q&A related to this product.
Question: How long does it take for this medication to become fully effective?
Answer: It may take about 3 weeks for the medication to become fully effective. Knowing the expected time frame for improvement helps set realistic expectations and encourages continued adherence during the initial period of therapy.
Question: Does imipramine cause weight gain?
Answer: Yes, imipramine can cause weight gain as a possible side effect. This weight gain may occur due to increased appetite or changes in metabolism. However, not everyone who takes imipramine will experience this effect.
