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We’ve provided several answers to questions related to Ingrezza (Valbenazine) , see some other helpful Q&A related to this product.
Question: What are the main side effects in patients with chorea due to Huntington’s disease?
Answer: Common side effects include excessive sleepiness, lethargy, sedation, hives, rash, and sleep problems. Awareness of these side effects allows for better management and prompt communication with healthcare providers.
Question: Who should not take this medication?
Answer: Patients with an allergy to valbenazine or any other ingredients in the capsules or Sprinkle capsules should not take it. Avoiding allergens prevents serious hypersensitivity reactions.
Question: What inactive ingredients are in the Sprinkle capsules?
Answer: The Sprinkle capsules contain silicified microcrystalline cellulose, isomalt, pregelatinized maize starch, hypromellose, magnesium stearate, polyvinyl alcohol, titanium dioxide, polyethylene glycol, talc, gelatin, and candurin silver fine. These ingredients help ensure the medication’s stability and make it easier to ingest.
Question: What is the active ingredient in this medication?
Answer: The active ingredient is valbenazine. Valbenazine is a selective vesicular monoamine transporter 2 (VMAT2) inhibitor, which helps reduce abnormal movements in conditions like tardive dyskinesia and Huntington’s chorea.
Question: What is the recommended storage temperature for the Sprinkle capsules?
Answer: The Sprinkle capsules should be stored between 20°C and 25°C (68°F and 77°F). Storing medication within the correct temperature range helps preserve its potency and quality.
Question: What is the protein binding percentage of the active ingredient?
Answer: The protein binding is 99%. High protein binding means most of the drug in the bloodstream is attached to proteins, affecting how much is available to work in the body and interact with other drugs.
Question: What is the approximate bioavailability of this medication?
Answer: The approximate bioavailability is 49%. Bioavailability refers to the proportion of the drug that enters circulation and is available to have an active effect, which is crucial for effective dosing.
Question: What is the formula of the active ingredient?
Answer: The chemical formula of the active ingredient, valbenazine, is C24H38N2O4. Knowing the formula helps healthcare professionals understand the compound's structure and potential interactions.
Question: What strengths are the capsules available in?
Answer: The capsules are available in 40 mg, 60 mg, and 80 mg strengths. Having multiple strengths allows for tailored dosing based on a patient's individual needs, which can optimize treatment outcomes.
Question: Can I drink alcohol while taking INGREZZA?
Answer: It is best to avoid drinking alcohol while taking INGREZZA (valbenazine). Alcohol can increase the risk of side effects such as drowsiness, dizziness, or trouble concentrating. Talk to your doctor for advice specific to your situation.