What is the most painful injection in IVF?
Merional (Menotrophin)
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Open May 06, 2026 - 10:15 AM
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May 06, 2026 - 10:15 AM
The most painful injection in IVF is often considered to be the progesterone in oil (PIO) intramuscular injection. This shot is given deep into the muscle, usually in the buttock, and can cause soreness, bruising, and discomfort due to the thick oil-based solution. Other injections, like subcutaneous hormone shots, are usually less painful.
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