Answer
Jun 23, 2026 - 10:41 AM
Trimbow is not usually associated with weight gain, and weight gain is not listed as a common or uncommon side effect in the UK patient leaflet’s side-effect list. The listed common effects include things like sore throat, runny/stuffy nose, oral thrush, hoarseness, headache, and urinary tract infection.
There are two ways it could be related indirectly:
- Fluid swelling: Trimbow lists swelling of the hands and feet as a very rare side effect. That can sometimes show up as a sudden increase on the scale.
- Steroid-type effects: Trimbow contains an inhaled steroid, beclometasone. Inhaled steroids usually have much less whole-body effect than steroid tablets, but NHS guidance says that long-term higher-dose beclometasone can rarely cause “moon face” and weight gain around the upper back or belly, which can be a sign of Cushing’s syndrome. Trimbow’s leaflet also notes that long-term high-dose inhaled corticosteroids can very rarely cause body-wide effects such as adrenal suppression, thinning bones, and cataracts.
Call your doctor soon if the weight gain is new, unexplained, or comes with ankle/foot swelling, worsening breathlessness, chest symptoms, puffy face, easy bruising, muscle weakness, or new high blood sugar. Do not stop Trimbow suddenly without medical advice, especially if it is controlling your COPD or asthma.
