Answer
Aug 19, 2026 - 11:51 AM
For nifedipine ER/XL, the most common significant side effect is peripheral edema — swelling of the ankles, feet, or lower legs. It happens because nifedipine dilates blood vessels and is more common at higher doses. In clinical trials of some extended-release formulations, edema occurred in roughly 18% at 30 mg, 22% at 60 mg, and 29% at 90 mg daily.
Other common effects include headache, flushing, dizziness/lightheadedness, and sometimes a faster heartbeat.
If the swelling becomes severe, rapidly worsens, or comes with shortness of breath, chest pain, or fainting, seek medical attention rather than assuming it's just a medication side effect.
If you're taking Adalat XL, I can also tell you the most common side effects specifically at 30 mg, 60 mg, or 90 mg.
